Traditional Chinese medicine for mole treatment is a traditional medicine project of the fifth batch of representative projects of intangible cultural heritage in Lianyungang City. Ke Jixian's traditional Chinese medicine hemorrhoid technology and art were inherited from Hu Bingzhang, a famous doctor who worked in the "Renhetang" pharmacy in Xiaguan, Nanjing during the Guangxu period of the late Qing Dynasty (about 1890). Hu Bingzhang was good at traditional Chinese medicine surgery and hemorrhoids. Relying on his ancestral and accumulated clinical experience, he devoted himself to developing a unique formula and made a hemorrhoid ointment "Jingzhi Ointment", which was widely circulated in Beijing and surrounding areas. In 1917, my grandfather Ke Yunpei drifted to Nanjing and was hired as a waiter at "Renhetang". My grandfather, who was diligent and studious, was favored by Hu Bingzhang, who accepted him as an apprentice, taught him skills, and treated him as his own son. A few years later, my grandfather followed Hu Bingzhang back to his hometown Baoying and opened the "Guyuezhai" pharmacy. In 1930, Hu Bingzhang passed away and my grandfather inherited his business. My father, Ke Jimin, learned medicine from his grandfather since he was a child. After liberation, he returned to Guannan and opened Yongsheng Pharmacy in Xinji to continue practicing medicine. In the practice of diagnosis and treatment, he adjusted the formula for treating hemorrhoids, changed the "Jingzhi Cream" to "Kuzhiling Powder", and also developed "Anal Fissure Cream" and "-Wet Diagnosis Cream", which have more significant curative effects. After graduating from high school, Ke Jixian followed his father to practice medicine and worked as a "barefoot doctor". He trained and studied in Guannan Medical School, Lianyungang Chinese Medicine School, etc., and obtained the qualification of practicing Chinese medicine physician. His medical theoretical knowledge and diagnosis and treatment skills have been greatly improved compared with his predecessors.