Suzhou is a place where Wu doctors gather and the pharmaceutical industry flourishes. In the middle of the Qing Dynasty, Lei Yunshang, a famous doctor from Wumen, studied and absorbed the essence of Wumen medical school, and brought Wumen medical skills to the extreme. He opened Songfentang Pharmacy in Changmen, Suzhou. Lei Yunshang lived in an era when the Wumen School of Warm Diseases was becoming increasingly mature. In the practice of treating warm diseases, doctors invented very small but very effective treatment prescriptions, among which the most representative one was Liushen Pills. Although medicine and pharmacy were basically separated at that time, Lei Yunshang combined medicine and pharmacy together. In his long-term clinical practice of selling medicine, Lei Yunshang mastered a large number of ancient prescriptions, accumulated a lot of folk prescriptions and single prescriptions, and conducted in-depth research on them. In particular, for emergency medicines for epidemics and medicines for common surgical diseases, he constantly modified the compatibility of precious spices and fine materials such as musk, rhinoceros horn, bezoar, antelope horn, pearls, and powerful medicines according to the principle of monarch, minister, assistant and envoy based on his clinical experience, and refined Liushen Pills and other prestigious medicines. Affected by the impact of modern Western medicine, people lack scientific knowledge about traditional Chinese medicine prescriptions, which has led to the decline of traditional Chinese medicine and directly affected the inheritance of Lei Yunshang's Liushen Pills making skills.